MicroRNA-770 affects proliferation and cell cycle transition by directly targeting CDK8 in glioma
نویسندگان
چکیده
منابع مشابه
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MicroRNAs (miRs) are a class of small non-coding RNAs that are involved in the regulation of gene expression, and in cancer development and progression. In the present study, miR-320 expression was found to be significantly reduced in glioma tissue in comparison with that in adjacent healthy tissues. In the present study, in vitro analyses demonstrated that overexpression of miR-320 inhibited c...
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Glioma is one of the most common, rapidly progressive and fatal brain tumors, and accumulating evidence shows that microRNAs (miRNAs) play important roles in the development of cancers, including glioma. Therapeutic applications of miRNAs in Ras-driven glioma have been proposed; however, their specific functions and mechanisms are poorly understood. Here, we report that miR-1301-3p directly tar...
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ژورنال
عنوان ژورنال: Cancer Cell International
سال: 2018
ISSN: 1475-2867
DOI: 10.1186/s12935-018-0694-9